Ferritin stimulation of a monokine inhibitor of lipopolysaccharide-augmented myelopoiesis is ferroxidase dependent.

نویسندگان

  • R Kreisberg
  • H E Broxmeyer
  • R N Moore
چکیده

Ferritin inhibition of myelopoiesis has been associated with intrinsic ferroxidase activity of heavy-chain ferritin and with production of a monokine inhibitor of lipopolysaccharide (LPS)-augmented monocytopoiesis. We report here that intrinsic ferroxidase activity of heavy-chain ferritin is required for stimulated production of the monokine inhibitor of LPS-augmented monocytopoiesis.

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عنوان ژورنال:
  • Infection and immunity

دوره 62 7  شماره 

صفحات  -

تاریخ انتشار 1994